Veli-Pekka Harjola Selected Research

Simendan (Levosimendan)

3/2020	Levosimendan Efficacy and Safety: 20 years of SIMDAX in Clinical Use.
1/2020	Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use.
12/2019	A pragmatic approach to the use of inotropes for the management of acute and advanced heart failure: An expert panel consensus.
11/2019	Short-Term Therapies for Treatment of Acute and Advanced Heart Failure-Why so Few Drugs Available in Clinical Use, Why Even Fewer in the Pipeline?
11/2019	Haemodynamic Balance in Acute and Advanced Heart Failure: An Expert Perspective on the Role of Levosimendan.
12/2018	Use of levosimendan in acute heart failure.
1/2018	Levosimendan in Acute and Advanced Heart Failure: An Appraisal of the Clinical Database and Evaluation of Its Therapeutic Applications.
11/2016	Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper.
9/2016	The role of levosimendan in acute heart failure complicating acute coronary syndrome: A review and expert consensus opinion.
7/2016	Effect of baseline characteristics on mortality in the SURVIVE trial on the effect of levosimendan vs dobutamine in acute heart failure: Sub-analysis of the Finnish patients.

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Veli-Pekka Harjola Research Topics

Disease

39	Heart Failure 06/2021 - 05/2006
25	Cardiogenic Shock 06/2022 - 05/2015
10	Myocardial Infarction 06/2022 - 03/2010
9	Stroke (Strokes) 01/2018 - 05/2013
8	Acute Coronary Syndrome 01/2021 - 01/2010
8	Atrial Fibrillation 01/2018 - 05/2013
6	Shock 10/2021 - 06/2005
6	Pulmonary Embolism 01/2021 - 05/2011
4	Heart Arrest (Cardiac Arrest) 08/2021 - 07/2016
4	Embolism (Embolus) 02/2015 - 05/2013
3	Hypotension (Low Blood Pressure) 10/2021 - 05/2015
3	Coronary Artery Disease (Coronary Atherosclerosis) 08/2021 - 02/2013
3	Hypothermia 08/2021 - 03/2016
3	Out-of-Hospital Cardiac Arrest 08/2021 - 03/2016
3	Coma (Comas) 08/2021 - 03/2016
3	Infarction (Infarctions) 01/2019 - 01/2010
2	Wounds and Injuries (Trauma) 06/2022 - 01/2010
2	Acidosis 01/2021 - 03/2017
2	Pulmonary Hypertension 03/2020 - 01/2020
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 03/2020 - 01/2020
2	Takotsubo Cardiomyopathy 03/2020 - 01/2020
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2020 - 01/2007
2	ST Elevation Myocardial Infarction 09/2019 - 11/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2017 - 08/2007
2	Confusion (Bewilderment) 03/2017 - 05/2015
2	Hemorrhage 10/2014 - 06/2013
1	Inflammation (Inflammations) 06/2022
1	Acute Kidney Injury (Acute Renal Failure) 02/2021
1	Frailty 01/2021
1	Heart Diseases (Heart Disease) 03/2020
1	Chest Pain (Chest Pains) 01/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Hypoalbuminemia 01/2019
1	Fatigue 12/2018
1	Lactic Acidosis 10/2018

Drug/Important Bio-Agent (IBA)

13	Simendan (Levosimendan)IBA 03/2020 - 01/2007
10	Biomarkers (Surrogate Marker)IBA 01/2021 - 10/2013
8	Lactic Acid (Lactate)FDA LinkGeneric 10/2021 - 05/2015
8	apixabanIBA 01/2018 - 05/2013
5	CreatinineIBA 01/2020 - 01/2007
5	CalciumIBA 12/2019 - 01/2007
5	Epinephrine (Adrenaline)FDA LinkGeneric 12/2019 - 07/2016
5	Warfarin (Coumadin)FDA LinkGeneric 10/2014 - 05/2013
4	pro-brain natriuretic peptide (1-76)IBA 01/2020 - 08/2007
4	Brain Natriuretic Peptide (Natrecor)FDA Link 11/2019 - 04/2008
4	TroponinIBA 06/2016 - 08/2008
3	XenonIBA 08/2021 - 03/2016
3	Growth Differentiation Factor 15IBA 01/2021 - 11/2019
3	MicroRNAs (MicroRNA)IBA 10/2020 - 01/2019
3	Troponin IIBA 01/2020 - 02/2014
3	Glucose (Dextrose)FDA LinkGeneric 04/2017 - 07/2016
2	RivaroxabanIBA 01/2021 - 01/2020
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 04/2008
2	Factor Xa InhibitorsIBA 01/2021 - 01/2020
2	SodiumIBA 01/2020 - 03/2010
2	Cystatin CIBA 01/2020 - 08/2007
2	Vasodilator Agents (Vasodilators)IBA 12/2019 - 01/2018
2	CatecholaminesIBA 12/2019 - 01/2018
2	DiureticsIBA 12/2019 - 01/2019
2	Dobutamine FDA LinkGeneric 12/2019 - 07/2016
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 12/2019 - 10/2018
2	Vasoconstrictor AgentsIBA 10/2018 - 09/2016
2	Potassium Channels (Potassium Channel)IBA 01/2018 - 12/2013
2	Troponin T (Troponin T1)IBA 11/2017 - 06/2005
2	Blood Glucose (Blood Sugar)IBA 01/2017 - 02/2013
1	Triggering Receptor Expressed on Myeloid Cells-1IBA 06/2022
1	Furosemide (Lasix)FDA LinkGeneric 06/2021
1	Lipocalin-2IBA 02/2021
1	proenkephalinIBA 02/2021
1	ProcalcitoninIBA 01/2021
1	C-Reactive ProteinIBA 01/2021
1	Insulin-Like PeptidesIBA 01/2020
1	procizumabIBA 01/2020
1	Insulin-Like Growth Factor Binding Protein 4IBA 01/2020
1	Dopamine (Intropin)FDA LinkGeneric 12/2019
1	Adrenergic beta-Agonists (beta-Adrenergic Agonists)IBA 12/2019
1	Milrinone (Primacor)FDA LinkGeneric 12/2019
1	Type 3 Cyclic Nucleotide PhosphodiesterasesIBA 12/2019
1	UlaritideIBA 11/2019
1	ElectrolytesIBA 01/2019
1	AlbuminsIBA 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Serum AlbuminIBA 01/2019
1	Oxygen (Dioxygen)IBA 12/2018
1	PotassiumIBA 03/2018
1	Bronchodilator Agents (Bronchodilators)IBA 01/2018
1	Clostridium perfringens epsilon-toxinIBA 01/2018
1	Cardiovascular AgentsIBA 01/2018
1	Mineralocorticoid Receptor AntagonistsIBA 01/2018

Therapy/Procedure

9	Therapeutics 01/2020 - 09/2013
5	Critical Care (Surgical Intensive Care) 03/2020 - 01/2008
4	Percutaneous Coronary Intervention 01/2021 - 04/2017
2	Length of Stay 01/2021 - 01/2019
2	Artificial Respiration (Mechanical Ventilation) 12/2020 - 03/2017
2	Counterpulsation (External Counterpulsation) 01/2020 - 01/2020
2	Noninvasive Ventilation 01/2018 - 03/2017
2	Resuscitation 05/2015 - 01/2008
1	Renal Replacement Therapy (Therapies, Renal Replacement) 12/2020
1	Catheters 12/2020
1	Heart Transplantation (Grafting, Heart) 01/2018